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Bioinformatics and genomic data : investigating a complex genetic disease -- Computational manipulation of DNA : genetic screening for disease alleles -- Sequence alignment : investigating an influenza outbreak -- Database searching and multiple alignment : investigating antibiotic resistance -- Substitution matrices and protein alignments : virulence factors in E. coli -- Distance measurement in molecular phylogenetics : evolution of mammals -- Tree building in molecular phylogenetics : three domains of life -- DNA sequencing : identification of novel viral pathogens -- Sequence-based gene prediction : annotation of a resistance plasmid -- Advanced gene prediction : identification of an influenza resistance gene -- Protein structure prediction and analysis : rational drug design -- Nucleic acid structure prediction : polymerase chain reaction and RNA interference -- Introduction to programming.