Normal view MARC view ISBD view

Guerois, Raphael

Protein design - Totowa Humana Press 2006 - xiv, 299p.

I DESIGN OF STRUCTURAL ELEMENTARY MOTIFS
1 Structure and Stability of the α-Helix: Lessons for Design
2 De novo Design of Monomeric β-Hairpin and β-Sheet Peptides
3 De novo Proteins From Binary-Patterned Combinatorial Libraries
4 Non-Protein Amino Acids in the Design of Secondary
Structure Scaffolds
5 Design and Synthesis of β-Peptides With Biological Activity

II DESIGN OF ENTIRE PROTEINS AND PROTEIN COMPLEXES
6 Design of Miniproteins by the Transfer of Active Sites Onto Small-Size Scaffolds
7 Consensus Design as a Tool for Engineering Repeat Proteins
8 Multiple Sequence Alignment as a Guideline for Protein Engineering Strategies
9 Sequence Search Methods and Scoring Functions
for the Design of Protein Structures
10 Prediction of Protein–Protein Interaction Based on Structure
11 Electrostatic Design of Protein–Protein Association Rates

III DESIGN OF AMYLOIDOGENIC POLYPEPTIDES AND AMYLOID INHIBITORS
12 Peptide Model Systems for Amyloid Fiber Formation: Design Strategies and Validation Methods
13 Protein Misfolding Disorders and Rational Design of Antimisfolding Agents

Index

ISBN: 9781588295859

Subjects--Topical Terms:
Protein Engineering
Proteins
Protein Conformation.
Protein Folding.

Dewey Class. No.: 660.6GUE